Post-Doctoral Fellow in Cancer Data Science | University of California Los Angeles - Military Veterans

at HERC - Southern California

Los Angeles, California

Post-Doctoral Fellow in Cancer Data Science University of California Los Angeles Requisition Number: JPF07220 The newly formed Cancer Data Sciences group at the UCLA David Geffen School of Medicine and UCLA Jonsson Cancer Centre is seeking a Post-Doctoral Fellow in Cancer Data Science: Algorithm Development. The successful candidate will have a PhD in computational biology, statistics, computer science or an equivalent quantitative discipline. They will be working with a broad team of quantitative analysts, including Statisticians, Data Scientists, Clinical and Basic Science trainees, and a broad range of collaborators. They will drive the development and application of new quantitative strategies to improve our understanding and ability to treat cancer, working with cutting edge molecular and imaging datasets. They will be passionate about generating high-quality results, linking development of new methods directly to cutting-edge datasets ranging from DNA, RNA and protein sequencing to clinical data, digital pathology and radiomics. They will have a track-record of success with peer-reviewed research demonstrating a careful approach that identifies potential confounders and sources of bias, and reproducible analyses with high-quality source-code. They will apply their skills to projects that will be customized to the technical, personal and career aspirations of the candidate, but can range from biomarker development to new technologies to systems biology to machine-learning. Our team works with a broad range of approaches ranging from convolutional neural networks through to statistical modeling and systems biology approaches. The methods developed will be executed at scale in robust computational pipelines to analyze patient cohorts ranging from tens to hundreds of thousands of individuals on both local HPC and cloud-based computing environments. This will entail working closely with others, including Bioinformaticians to ensure reproducibility and generalizability. Our datasets comprise petabytes, and are growing rapidly, linked to key clinical endpoints and covering almost all tumour types. While a strong background in biology or cancer biology is beneficial, for this role very strong quantitative skills are essential. Strong scientific communication skills, orally and in writing as well as in designing high-quality scientific data-visualizations, are very valuable, and significant training and support will be given in this area. The successful candidate will be helping us perform research that will transform the lives of cancer patients. Your responsibilities will be to use your biological and data science skills to analyze large datasets, including identification of key features using established or new pipelines, statistical and machine-learning analyses, data visualization, and written & oral reporting to translational, biologic, translational and clinical teams. Your work may focus on a single tumour type, or may cover a broad range, focusing on a subset of data types. You may work with molecular (WGS, panel-sequencing, RNA-Seq, proteomic) and/or imaging (digital pathology, radiomic) data, and practical experience in one of these two areas is a major asset. You will typically have one to two major and potentially some minor projects at any point in time. We are in a rapid growth-phase, and the successful candidate will be involved in hiring of new team members, and supporting their training and on-boarding. Beyond your strong inter-personal skills and computer science background, you will have experience with implementation skills at least one of C/C++, R, Perl or Python. You will be comfortable in UNIX/Linux environments and producing well-documented code. A core background in statistics is key, and supplementation with advanced understanding of time-to-event analyses, Bayesian statistics or machine-learning is beneficial. Experience with cloud-computing or HPC is a major asset. Recent publications from previous trainees in this team have included: Sinha A et al. (2019) 'The Proteogenomic Landscape of Curable Prostate Cancer' Cancer Cell (PMID: 30889379) Chen S et al. (2019) 'Widespread and Functional RNA Circularization in Localized Prostate Cancer' Cell (PMID: 30735634) Bhandari V et al. (2019) 'Molecular Landmarks of Tumour Hypoxia' Nature Genetics (PMID: 30643250) Haider S et al. (2018) 'Pathway-Based Biomarkers Enable Cross-Disease Biomarker Discovery' Nature Communications (PMID: 30420699) Espiritu SMG et al. (2018) 'The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression' Cell (PMID: 29681457) Cultural North Star. The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what's right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at . To apply, please visit: The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy, jeid-092b6fae4f7d0d4188ff8f52bace4f70

Los Angeles, California

Southern California HERC, established in 2003, is a non-profit organization composed of a diverse group of colleges and universities, and research, medical, and cultural institutions. Our institutions are committed to diversity, equity, and inclusion in the recruitment process and providing a work environment sensitive to work/life balance. We also understand that employment decisions often involve two careers and offer state of the art dual career resources and solutions. SoCal HERC includes members from the Central Coast, Los Angeles, Orange County, Inland Empire, and San Diego.

HERC is a gateway to more jobs in higher education and related fields than any other website. HERC provides job seekers with comprehensive and transparent access to job opportunities, daily job alerts, career advice news and webinars, dual career support, and regional multicultural resources to help with relocating to a new community.

SoCal HERC Member Institutions:

Antioch University, Azusa Pacific, University Cal Tech

CSU Fullerton, CSU Northridge,  CSU San Bernardino 

Cedars-Sinai Medical Center, Chapman University, Citrus College

Concordia University Irvine, Grossmont-Cuyamaca CCD, Kaiser Permanente School of Medicine 

Loyola Marymount University, MiraCosta Community College, Mount St. Mary’s University

North Orange County CCD, Occidental College,  Pacific Oaks College & Childrens School 

Point Loma Nazarene University, San Diego State University, Soka University of America

The Claremont Colleges, The Salk Institute for Biological Sciences, UC Path Center

UC Irvine, UCLA, UC Riverside

UCSD, University of Redlands, University of San Diego

University of Southern California, Vanguard University, Whittier College

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