Durham, North Carolina

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Summary Description: 

Performs a variety of complex technical duties involved in conducting laboratory tests, experiments and determinations in support of Duke University research operations. 

 

Responsibilities:

• Performs a variety of complex technical duties involved in conducting physical, chemical, biological and other research laboratory tests, experiments and determinations to obtain data for research purposes; compile, analyze, document and draw tentative conclusions from experimental results. 

• Confer with principal investigator to review work assignments and develop plans for research experiments; make minor modifications to existing laboratory procedures and techniques to meet the needs of the particular equipment as required. 

• Review laboratory methods manual, scientific journals, abstracts and other literature for information applicable to research experiments. 

• Determine and set up instruments, material and apparatus and operate laboratory equipment required for specific tests. 

• Obtain, prepare, mount and stain tissue, blood and other substances for microscopic examination. 

• Prepare culture media, chemicals, reagents and solutions. 

• Maintain sufficient inventory of material, supplies and equipment for performance of duties; clean and maintain laboratory equipment. 

• Review work of lower level laboratory personnel within designated areas and assist in training new personnel. 

• Perform other related duties incidental to the work described herein. 

• Review completeness or accuracy of the work of others

• Give recommendations, advice or guidance to others

• Review expenses related to materials and supply, and confirm the grant-budget monthly reports.

• Generating reports of results

• Create and maintain laboratory records.(protocols and biological materials)

 

Skills:

• Knowledge/experience in various methods of molecular biology, analysis of gene expression, genetics, functional genomics, cell biology and bioinformatics.  For example: samples receipt and handling, RNA-seq, ATAC-seq, WG genotyping, single-cell omics, shRNA, real-time PCR, RNA handling, RT-PCR, qPCR, cell-culture, hiPSC work, genome editing by CRISPR-Cas9, viral transduction, transfections, luciferase reporter assays, GFP reporter assay and immunofluorescence, RNA and DNA extraction, cloning, plasmids construction, plasmids preps, protein extraction and analysis, nuclear extraction, chromatin immuno-precipitation, electrophoretic mobility shift assay, DNA-binding protein purification, sequence analysis, genotyping, wide genomic comparison analysis across evolution, computer analysis of TF binding sites, bioinformatic tools for genomic analysis.​

 

GOALS AND OBJECTIVES

Research Analyst I will face numerous challenges in the first twelve to eighteen months and will be expected to respond and maintain flexibility under those conditions.  

 

CANDIDATE QUALIFICATIONS

Education: 

Work requires a bachelor's degree in botany, biology, zoology or other science related scientific field. Training in genetic and molecular biology methods.

Experience: 

Three years and above in a genetic and molecular biology lab work. 

OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE.

     

     

     

     

    Minimum Qualifications

     

    Education

    See job description for education requirements.

    Experience

     

    See job description for requirements.

     

    Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

     

    Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

     

    Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

     

    Durham, North Carolina

    As a world-class academic and health care system, Duke Health strives to transform medicine and health locally and globally through innovative scientific research, rapid translation of breakthrough discoveries, educating future clinical and scientific leaders, advocating and practicing evidence-based medicine to improve community health, and leading efforts to eliminate health inequalities.

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