Durham, North Carolina

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Neurobiology

 

100% grant funded

 

Job Description
Occupational Summary

Perform a variety of complex technical duties involved in conducting laboratory tests, experiments and determinations in support of Duke University research operations.
 

Work Performed

  • Perform a variety of complex technical duties involved in conducting physical, chemical, biological and other research laboratory tests, experiments and determinations to obtain data for research purposes; compile, analyze, document and draw tentative conclusions from experimental results.
  • Execute and troubleshoot all facets of mouse model of epilepsy.  This includes performing stereotaxic surgery for placement of injection cannulas, recording electrodes, and viruses; constructing novel recording electrode array on headmounts with preamplifiers; deploying novel computer software for detection of seizures using EEG and  video data; performing repeated intravenous injections into retroorbital sinus of adult mice.
  • Assume responsibility of ordering supplies and equipment for lab members, specifically aligning the order with proper grant code.   Place and track orders at the request of lab member.  Maintain sufficient inventory of material, supplies and equipment for performance of duties; clean and maintain laboratory equipment.  Set up instruments, material and apparatus and operate laboratory equipment required for specific tests. Notify lab members of lab meetings and presenters at lab meetings on weekly basis.
  • Serve as point person for interaction with DLAR and assure laboratory procedures are conducted in accord with IACUC approved protocol.  Prepare amendments to IACUC  protocol as needed.
  • Confer with principal investigator to review work assignments and develop plans for research experiments; make minor modifications to existing laboratory procedures and techniques to meet the needs of the particular equipment as required. Review laboratory methods manual, scientific journals, abstracts and other literature for information applicable to research experiments.
  • Conduct biochemical assays including Elisa, Fluorescent resonant energy transfer, Western blotting.    Prepare and maintain primary cultures of rat and mouse cortical neurons and glia. Prepare culture media, chemicals, reagents and solutions.  Obtain, prepare, mount and stain tissue for microscopic examination.
  • Perform other related duties incidental to the work described herein.

 

Minimum Qualifications
Education

Work generally requires skills acquired through the completion of a bachelor's degree in neurobiology, chemistry, biology, or similar science related scientific field.

 

Experience
Work requires two years of experience in a research laboratory.   A related master's degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE.

 

 

 

 

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

 

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

 

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

 

Durham, North Carolina

As a world-class academic and health care system, Duke Health strives to transform medicine and health locally and globally through innovative scientific research, rapid translation of breakthrough discoveries, educating future clinical and scientific leaders, advocating and practicing evidence-based medicine to improve community health, and leading efforts to eliminate health inequalities.

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