Durham, North Carolina

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Occ Summary 

Perform a variety of complex technical duties involved in conducting laboratory tests, experiments and determinations in support of Duke University research operations. 

Work Performed 


Manage lab projects 

Perform a variety of technical duties involved in conducting physical, chemical or biological tests, experiments and determinations to obtain data in support of research-oriented activities; compile and document procedures and results. Handle and use mice as an experimental model of human disease. 


Establish work procedures 

Determine and set up instruments, material and apparatus and operate laboratory equipment required for specific tests. Establish appropriate calibration and/or repair of equipment if required. 

· Prepare culture media, chemicals, solution s and reagents. 

· Confer with principal investigator to review work assignments and develop plans for research experiments. 

· Re view laboratory methods manual, scientific journals, abstracts and other literature for information applicable to research experiments. 

· Carry out experimental protocols 

· Use computer-based data management and computer-based analysis programs. Employee will analyze data, present graphs and analyses and prepare written reports. 

· Using computer-based buy at Duke and other systems, initiate and carry out- ordering supplies, arrange data uploading to protected files, etc that are typical for a research-based laboratory 

· Supervise the work of lower level employees and students engaged in data collection and assist in tabulation and proper storage of data, establish work procedures including assisting with writing of appropriate protocols, results of experiments, data analyses 

· Direct supervision and training of undergraduate students in the proper u se of equipment, proper handling and use of experimental mice, oversee safety 


Carry out Animal based care and experiments Handling, breeding and maintaining mice in an established colony containing multiple genetic strains of mice- this includes skills in animal husbandry; animal identification and tracking, animal gender identification; and using various techniques to genotype mice 

· Harvesting tissue from mice 

· Injection of mice 

Behavior studies on mice 

· Approved Euthanasia of mice 

· Perfusion of mouse brain 

· Storage of mouse tissue and maintenance of data records for each mouse 

· Prepare tissue specimens from mouse brain or other tissues for use in microscopy, or other critical techniques 


Molecular biology/biochemical analytic skills 

standard lab techniques such as but not inclusive to • Quantitative (real time) PCR, gene arrays • Immunoblotting (western) including LICOR techniques • ELISA 

• Protein assays 


· Oversee other technical support, including students and other lower level employees 

· Interact with vendors to purchase supplies, equipment etc. 

· Place and receive orders for lab purchases 

· Maintain standards for cleanliness and order in the lab 

· Other duties as assigned 


Knowledge, Skills and Abilities 



Minimum Qualifications 



Work generally requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field. 



None required above education/training requirement. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE




Minimum Qualifications




Work generally requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.




None required above education/training requirement. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE


Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Durham, North Carolina

As a world-class academic and health care system, Duke Health strives to transform medicine and health locally and globally through innovative scientific research, rapid translation of breakthrough discoveries, educating future clinical and scientific leaders, advocating and practicing evidence-based medicine to improve community health, and leading efforts to eliminate health inequalities.

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