Durham, North Carolina

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.



Occupational Summary

The Karra lab is seeking a Lab Research Analyst (LRA1) to work on projects related to resolving growth niches in the heart during development, regeneration, and disease.  The LRA1 will be mentored directly by Dr. Karra towards their career goals.  The position is expected to encompass work with transgenic mice, histology and microscopy, and next generation sequencing data streams.


Work Performed

The LRA 1 will conduct a variety of investigations in the planning, development and implementation of experimental procedures and specialized laboratory techniques within the overall scope of the research projects in the Karra Lab.  This position will be focused on defining mechanisms of cardiac growth and disease.

Specific tasks and techniques will include, but are not necessarily limited to, mouse husbandry and breeding, injection of mice with experimental reagents, harvesting of tissue specimens from mice, histologic processing of tissues, microscopy, cell culture, and standard molecular biology techniques.  In addition, the LRA1 is expected to help maintain regulatory compliance, maintain inventories, and assist with ordering for the laboratory.

The LRA 1 will collect information and data through observation and experimentation. The LRA1 will maintain detailed records of tests performed and report laboratory test results to the PI and other laboratory personnel.  The LRA1 will then confer with principal investigator to interpret results and discuss subsequent experiments.


The LRA1 will evaluate and interpret collected data to be presented to the PI and laboratory personnel.  The LRA1 will assemble data into figures for presentations and publications.


The LRA1 will Supervise, train and instruct residents, interns, students or lower level personnel in laboratory techniques and procedures.



Perform other related duties incidental to the work described herein.

In addition, it is expected that the LRA1 will review journals, abstracts and scientific literature to keep abreast of the latest developments in the field, as well as obtaining information regarding previous experiments, to aid in the design and development of original procedures and techniques.


Required Qualifications at this Level


Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.



Work requires two years of research experience. A related master's degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience.






The intent of this job description is to provide a representative and level of the types of duties and responsibilities that will be required of positions given this title and shall not be construed as a declaration of the total of the specific duties and responsibilities of any particular position. Employees may be directed to perform job-related tasks other than those specifically presented in this description.

Essential Physical Job Functions


Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.





Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Durham, North Carolina

As a world-class academic and health care system, Duke Health strives to transform medicine and health locally and globally through innovative scientific research, rapid translation of breakthrough discoveries, educating future clinical and scientific leaders, advocating and practicing evidence-based medicine to improve community health, and leading efforts to eliminate health inequalities.

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