Madison, Wisconsin

Job Summary: This position will be a member of the Webb Research Group which uses animal and cellular models to study rare pediatric diseases. Ongoing work in the laboratory includes studying mitochondrial disorders, a recently discovered ataxia, and congenital facial weakness. The Scientist I will identify research problems, design research methodologies, perform and supervise research, prepare the results for presentation and scholarly publications, and assist with grant preparation and submission. The position will focus on either stem cell work or mouse work. Duties will vary depending on the project designated to the Scientist, but may include DNA, RNA, and protein isolation and characterization, directed mutagenesis, cloning, viral vector preparation, tissue culture techniques, and 3D engineered tissue culture. The Scientist I will conduct research including all aspects of experimental design, execution, data analysis, and preparation for oral and written communication and will supervise research staff in the conduction of day- to-day research within the laboratory. The candidate will also analyze and interpret the data obtained from those studies, participate in laboratory meetings, and have the opportunity to prepare and write manuscripts for publication. Responsibilities: Identifies research problems, designs research methodologies, performs research, and helps to prepare the results for presentation to professional organizations or for scholarly publications to help advance research. 20% Assists with the identification of research problems and the development of research methodologies and procedures 50% Collects and analyzes research data, conducts experiments and interviews, and documents results according to established policies and procedures under general supervision and limited responsibility 5% Conducts literature reviews, prepares reports and materials, and disseminates information to appropriate entities 5% Attends and assists with the facilitation of scholarly events and presentations in support of continued professional development and the dissemination of research information 5% Writes or assists in developing grant applications and proposals to secure research funding 15% Serves as a main point of contact and liaison with internal and external stakeholders providing information and representing the interests of a specialized research area Institutional Statement on Diversity: Diversity is a source of strength, creativity, and innovation for UW-Madison. We value the contributions of each person and respect the profound ways their identity, culture, background, experience, status, abilities, and opinion enrich the university community. We commit ourselves to the pursuit of excellence in teaching, research, outreach, and diversity as inextricably linked goals. The University of Wisconsin-Madison fulfills its public mission by creating a welcoming and inclusive community for people from every background - people who as students, faculty, and staff serve Wisconsin and the world. For more information on diversity and inclusion on campus, please visit: Diversity and Inclusion Education: Required Terminal Degree Qualifications: -Mouse husbandry OR hiPSC experience required. -Minimum of 2 years of research experience in molecular biology, genetics, or stem cell work. -Significant experience in the following fields and knowledge of related methods is essential: cell culture, mouse models of disease, Western blotting, tissue processing, and immunohistochemistry. The ideal candidate will have the following experience: Mouse work: - Experience setting up timed matings - Experience with mice euthanasia - Experience dissecting E9.5 to E14.5 embryos - Experience embedding embryo samples & preparation for cryosectioning would be an exceptional candidate - Experience genotyping and maintaining mouse colony records hiPSC work: - Cell culture experience with iPSC and hiPSC lines - Experience maintaining, expanding, and freezing lines - Experience differentiating iPSC lines into neurons (or other cell types) - Experience developing organoids would be an exceptional candidate - Experience with cell picking would be an exceptional candidate Other Experience (Please describe if you have experience with the following): - Experience performing Western blotting - Experience performing cryosectioning - Experience with immunohistochemistry - Experience with fluorescent and confocal microscopy - Experience with FACS cell sorting General Requirements: - Excellent written and verbal communication skills - Experience working with undergraduate students and summer students preferred - Ability to problem solve, discuss and interpret results, and comfortable with some independence COVID-19 Considerations: UW-Madison continues to follow necessary health and safety protocols to protect our campus from COVID-19. All employees remain subject to the COVID-19 Workplace Safety Policy: https://policy.wisc.edu/library/UW-5086 . Please visit https://covidresponse.wisc.edu for the most up-to-date information. Work Type: Full Time: 100% It is anticipated this position requires work be performed in-person, onsite, at a designated campus work location. Appointment Type, Duration: Ongoing/Renewable Salary: Minimum $60,000 ANNUAL (12 months) Depending on Qualifications The starting salary for the position is $60,000 but is negotiable based on experience and qualifications. Employees in this position can expect to receive benefits such as generous vacation, holidays, and paid time off; competitive insurances and savings accounts; retirement benefits Additional Information: The successful applicant will be responsible for ensuring eligibility for employment in the United States on or before the effective date of the appointment. University sponsorship is not available for this position. Please be aware that successful applicants are responsible for ensuring their continuous eligibility to work in the United States (i.e. a citizen or national of the United States, a lawful permanent resident, a foreign national authorized to work in the United States without the need of employer sponsorship) on or before the effective date of appointment. This position is an ongoing position that will require continuous work eligibility. If you are selected for this position you would have to provide proof of work authorization and eligibility to work. How to Apply: To apply for this position, please click on the "Apply Now" button. You will be asked to upload a resume and cover letter as a part of the application process. Please ensure that the resume and cover letter address how you meet the minimum/preferred qualifications for the position. You will also be asked to provide three professional/supervisor references during the application process. References will not be contacted without prior notice. Contact: Ashley Royston ashley.royston@fammed.wisc.edu 608-890-3746 Relay Access (WTRS): 7-1-1 (out-of-state: TTY: 800.947.3529, STS: 800.833.7637) and above Phone number (See RELAY_SERVICE for further information. ) Official Title: Scientist I(RE043) Department(s): A536759-MEDICAL SCHOOL/PEDIATRICS/PULMONARY Employment Class: Academic Staff-Renewable Job Number: 258446-AS   The University of Wisconsin is an Equal Opportunity and Affirmative Action Employer. We promote excellence through diversity and encourage all qualified individuals to apply. If you need to request an accommodation because of a disability, you can find information about how to make a request at the following website: https://employeedisabilities.wisc.edu/disability-accommodation-information-for-applicants/ Employment will require a criminal background check. It will also require you and your references to answer questions regarding sexual violence and sexual harassment. The University of Wisconsin System will not reveal the identities of applicants who request confidentiality in writing, except that the identity of the successful candidate will be released. See Wis. Stat. sec. 19.36(7). The Annual Security and Fire Safety Report contains current campus safety and disciplinary policies, crime statistics for the previous 3 calendar years, and on-campus student housing fire safety policies and fire statistics for the previous 3 calendar years. UW-Madison will provide a paper copy upon request; please contact the University of Wisconsin Police Department .

Madison, Wisconsin

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