Greenfield, Indiana

This Sr. Research Scientist - Cell Culture position directly supports the Technical Development (TD) Organization in its mission to deliver Innovation, Characterization and Control. The primary responsibilities of this role are to drive the next generation Mammalian Cell Culture Strategies to characterize and control Product Quality and to develop the Robust Upstream Processes needed to advance early and late phase biomolecules portfolio. The cell culture scientist will provide hands-on, day-to-day technical leadership and support of all upstream lab activities covering the broad scope of large molecule portfolio with initial emphasis on delivering therapeutic monoclonal antibody platforms.
  • Job Title: Sr. Research Scientist - Cell Culture
  • Location: Greenfield, Indiana (Indianapolis Metro Area)
  • Salary: ~105,000 + Benefits (401k, relocation package, bonus, etc.)


Responsibilities will include but are not limited to experimental design and analysis of cell culture operations (fed-batch and perfusion), technical program leadership, lab supervision, collaboration with internal and external partners and technology transfer with manufacturing partners. This role’s deliverables will additionally include authoring and executing protocols, batch records and technical reports. 

Upstream Process Development:

  • Provide subject matter expertise to the mammalian cell culture processes and seed train expansion. Leverage knowledge/experience to accelerate and optimize the protein production.
  • Build a upstream platform based upon technical innovation, solid business understanding, and an appropriate phase appropriate risk approach
  • Introduce new techniques and technologies. Keep pace with the expertise in the field and the competitive landscape
  • Support Vaccines and Biotherapeutics process development
  • Provide Individual Contributor expertise with personal development into a leading strategic influencer
  • Development high throughput bioreactor capabilities to support:
    • Productivity optimization
    • Cell Culture Design Space definition
    • Discovery enablement (material supply)
    • Establishing robust Control Strategy
    • Media development and optimization
    • Cell Culture commercialization
  • Work effectively across all R&D teams, manufacturing and with external collaborators
  • Facilitate technology transfer with internal and external partners
  • Author technical reports, SOP’s, batch records and tech transfer documents


  • M.S. with 4yrs of combined academic and/or professional experience -OR- PhD in engineering, biochemistry or other biotechnology related degree.
  • Experience working with mammalian cell culture of large molecule product streams (Monoclonal Antibodies, Proteins, Antigens).

You should know: Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.

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Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law.


Greenfield, Indiana

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