Senior Research Technician - Molecular Microbiology | Washington University in St. Louis - Military Veterans

at Herc - Missouri

St. Louis, Missouri

Scheduled Hours 40 Position Summary This position independently performs complex research studies, experiments and assays. The Stallings Laboratory is seeking a highly motivated individual to assist with innovative research in the areas of microbiology, immunology, molecular biology, biochemistry, and antibiotic discovery. In the Stallings Laboratory, we dissect the molecular details of Mycobacterium tuberculosis pathogenesis, from the perspective of both the host and the pathogen. We use a combination of genetics, biochemistry, cell biology, and animal models of disease to seek better understanding of how M. tuberculosis defends itself against host immune attacks and antibiotic therapy, as well as what immune responses are required to control M. tuberculosis infection. We have identified a number of mycobacterial proteins that function as mediators of mycobacterial stress responses and are required for pathogenesis. In particular, we are currently focusing on how regulation of gene expression, DNA replication, and respiration allow M. tuberculosis to adapt to host-derived stresses and antibiotic therapy. In addition, we have discovered multiple host proteins and immune pathways that are required to control M. tuberculosis infection and prevent active tuberculosis disease. In particular, our studies highlight the importance of the innate immune response in regulating neutrophil-predominated inflammation to prevent tissue damage. In addition to these mechanistic studies, the lab is working to apply our basic science findings to the treatment of disease in humans. The position requires working in a Biosafety Level 3 laboratory and working with mice, including small animal procedures and genotyping. Job Description Primary Duties & Responsibilities Performs complex analysis/projects according to research protocols, explaining methods and procedures to other technicians. Provides for data entry and current data files on research projects.  Monitors data to ensure consistent quality. May perform preliminary statistical analysis of data. Assures compliance with established safety procedures and maintains required documentation on laboratory and specimen conditions. Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures. Assists in the training and development of technicians, acting as a group leader. Working Conditions This position works in a laboratory environment with potential exposure to biological and chemical hazards.  The individual must be physically able to wear protective equipment, work in a Biosafety Level 3 laboratory and to provide standard care to research animals. Preferred Qualifications Demonstrated ability to work independently and communicate with laboratory staff and investigators.  Ability to maintain complete and organized records/reports.  Working knowledge of computer software and general lab equipment. Required Qualifications Masterâ™s degree with two years of experience in a laboratory setting or an equivalent combination of education and experience equaling seven years. Grade R08-H Salary Range $17.34 - $29.50 / Hourly The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget. Pre-Employment Screening All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening. Benefits Statement Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits. EEO/AA Statement Washington University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration without regard to an individualâ™s sex, race, color, religion, age, disability status, protected veteran status, national or ethnic origin, gender identity or expression, sexual orientation. Women, minorities, protected veterans and the disabled are strongly encouraged to apply. Diversity Statement Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply. Applicant Instructions When you are ready to apply, creating an account only takes a minute. Your account creates a candidate home page which we will use to communicate with you and allows you to apply for jobs and view your application statuses. The first page of the application offers two âQuick Applyâ? options. 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