Durham, North Carolina

School of Medicine:

 

Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

 

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

 

This position will be involved in conducting simulation studies for methodology development, genetic data analysis for various human complex traits including Alzheimer disease, and preparation of summary reports (statistical methods, tables, and figures) and manuscripts.

 

Responsibilities

 

  • Work with Dr. Li to develop statistical analysis plan (SAP) for each project.
  • Conduct simulation studies under the guidance of senior statisticians to evaluate Type I error and statistical power for the new methods developed by Dr. Li’s team. Majority of simulation programs will be written in R.
  • Collaborate with other members in the team to develop R packages or standalone programs for the new methods for data analysis.
  • Conduct genetic or genomic data analysis for the study on the age-at-onset of Alzheimer disease, including common and rare variant association, polygenic risk score, Mendelian Randomization analysis, etc.  
  • Conduct genetic and biomarker analysis for clinical outcomes of osteoarthritis (OA).
  • Prepare summary report and maintain excellent documentation for each project.
  • Write analysis programs including SAS, R, PLINK, UNIX shell scripts with informative annotations.
  • Apply any related bioinformatic tools to genetic projects.
  • Assist with manuscript development and grant proposal preparation.
  • Perform other related duties and special projects as requested. 

 

Education/Training:

Work requires a minimum of a Master's degree in (bio)statistics or related field and no relevant experience, or a bachelors degree in (bio) statistics or related field and 2 years relevant experience, or an equivalent combination or relevant education and/or work experience.

Experience:

 

 

OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE

Prior contribution to analysis of research projects, a working knowledge of SAS, and solid command of the English language is required.

 

Experience

Prior contribution to statistical analysis of genetic and/or clinical research projects, a working knowledge of R, SAS, and UNIX/LINUX system, and solid command of the English language is required.

 

Skills / Knowledge

  • Strong knowledge in basic and advanced statistics, including generalized linear model and survival models 
  • Proficiency in UNIX/LINUX system (e.g. sufficient knowledge of writing scripts) and R
  • Training in statistics, biostatistics, or statistical genetics are required
  • Individual with strong interests and motivation in learning statistical genetics is preferable 
  • Good communication and writing skills
  • Proficiency with Microsoft Office (Word, Excel, PowerPoint), and familiarity with SQL
  • Ability to format high dimensional data for standard statistical software
  • Ability to explore new analysis tools (standalone programs or R packages) for data analysis
  • Strong organizational skills and ability to meet deadlines (e.g. grant application, conference abstract submission and presentation)
  • Strong documentation skills to generate detailed documentation for each project
  • Initiative to acquire new skills and knowledge
  • Ability to work on multiple projects simultaneously

 

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

 

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

 

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

 

Durham, North Carolina

As a world-class academic and health care system, Duke Health strives to transform medicine and health locally and globally through innovative scientific research, rapid translation of breakthrough discoveries, educating future clinical and scientific leaders, advocating and practicing evidence-based medicine to improve community health, and leading efforts to eliminate health inequalities.

Similar jobs