Senior Scientist, Analytical Research & Development - NMR Structure Elucidation - Military Veterans

at Merck & Company

South San Francisco, California

Job Description

As a Senior Scientist in Analytical R&D, Analytical Enabling Technologies, your efforts will be focused on enabling the discovery of new candidate molecules in our biologics and small molecule portfolios, including emerging modalities and bioconjugates.  Key deliverables will include the invention, implementation, and execution of analytical measurement technologies that may accelerate the pace of discovery research and influence molecular design.  The successful candidate must be able to collaborate in a dynamic, integrated, and multidisciplinary team environment which bridges early discovery research with a line of sight to clinical scale manufacturing.  We leverage a broad range of tools (e.g., NMR, spectroscopic, chromatographic, mass spectrometry, etc.) to influence selection of candidate molecules, enhance scalability and robustness, and to identify and contribute to new technology research and data analyses related to the discovery of novel therapeutics. Work performed in the NMR group includes, but is not limited to, structure elucidation and characterization, stereochemistry determination, mechanism elucidation, etc.

The ideal candidate will have knowledge in the discovery and development paradigms for pharmaceutical products, and proficiency in more than one of the following areas: NMR, chromatography, mass spectrometry, and lab automation. Strong fundamental knowledge in recent advances in analytical technologies is highly desired. Applicants must have effective organizational, multi-tasking, oral / written communications skills, have demonstrated scientific leadership and a desire to conduct research and publish.  As a member of our team, you will be joining scientific problem solvers who are dedicated to creating the life-changing medicines of tomorrow.

Position Qualifications:

Education Minimum Requirement:  

  • Ph.D. (or expected by 2021) in chemistry, biochemistry, biophysics, or equivalent with an emphasis in NMR techniques.

Required Experience and Skills:

  • 1+ years' experience in NMR spectroscopy.

  • 1+ years’ experience in a second analytical characterization method (e.g., Chromatography, Spectroscopy, Mass Spectrometry).

Preferred Experience and Skills:

  • 3+ years of experience in structure elucidation with a proven track record of accomplishments in the area of small organic molecule structure elucidation (e.g., natural products, saccharides, pharmaceuticals, etc.).

  • Strong knowledge of organic chemistry, biochemistry or physical chemistry; experience in a medicinal or process chemistry environment is desirable.

  • Comprehensive knowledge of NMR instrumentation, methodology and software.

  • Chromatography (e.g. UPLC, cIEF, SEC, HIC, IEX).

  • Spectroscopy (e.g. Raman, Infrared, UV-Vis, Fluorescence, etc.).

  • Mass Spectrometry (structural elucidation, peptide mapping).

  • Experience with high throughput analytical methods.

  • Experience with monoclonal antibodies and/or bioconjugates.

  • Programming experience (e.g., Python, R, Mathematica, Matlab, Labview, etc.).

  • Lab automation and technology hardware / software integration.

  • Excellent track record of publications, posters, and speaking engagements.

  • Excellent oral and written communication skills.

  • Excellent interpersonal, collaboration, and teamworking skills.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe. 

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

Invent. Impact. Inspire.


In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster

EEOC GINA Supplement​

OFCCP EEO Supplement

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:




VISA Sponsorship:


Travel Requirements:

Flexible Work Arrangements:


Valid Driving License:

Hazardous Material(s):

Number of Openings:


Requisition ID:R118422

South San Francisco, California

Today's Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, and consumer care and animal health products, we work with customers and operate in more than 140 countries to deliver innovative health solutions. We also demonstrate our commitment to increasing access to healthcare through far-reaching policies, programs and partnerships. For more information, visit

Similar jobs