Bethesda, Maryland

Join the HJF Team!

HJF is seeking a Scientist II to support the Murtha Cancer Center (MCC), located at the Uniformed Services University in Bethesda, MD. HJF provides scientific, technical and programmatic support services to the Murtha Cancer Center. U.S Citizenship is required.

The American Genome Center at the Uniformed Services University of the Health Sciences (USUHS) seeks a lead Scientist to coordinate and execute large-scale genomics tasks for the APOLLO Network (proteomics.cancer.gov/programs/apollo-network) projects in support of the Murtha Cancer Center (MCC). The Scientist will be responsible for directing a team of research associates in completing next-generation sequencing-based profiling projects for pan-cancer studies. The Scientist will contribute to scientific, technical and programmatic development of molecular oncology-based goals of the collaborative network.

The Applied Proteogenomics OrganizationaL Learning and Outcomes (APOLLO) network is a collaboration between NCI, the Department of Defense (DoD), and the Department of Veterans Affairs (VA) to incorporate proteogenomics into patient care as a way of looking beyond the genome, to the activity and expression of the proteins that the genome encodes. The emerging field of proteogenomics aims to better predict how patients will respond to therapy by screening their tumors for both genetic abnormalities and protein information, an approach that has been made possible in recent years due to advances in proteomic technology.

The DoD agency leading the APOLLO network is the Murtha Cancer Center (MCC) at the USUHS in Bethesda, Maryland. The MCC is a modern, patient-centric, tri-service military healthcare facility. Its comprehensive core of military and civilian oncologists and other cancer-trained clinicians and researchers provide multidisciplinary cancer-care delivery and patient-family support services. Our Cancer Center, the only DoD Cancer Center of Excellence within the Military Health System, offers its patients access to cutting-edge cancer diagnostic and treatment technologies.

Responsibilities:
  1. Plans, conducts and executes next-generation sequencing-based profiling projects for APOLLO Network investigators. Contributes and formulates experimental hypotheses and designs experimental protocols to match defined APOLLO outcomes. (45%)
  2. Establishes, updates, and maintains standard operating procedures for existing and novel sequencing workflows for oncology-based applications. Provides training guidance for technical staff in sequencing workflows. (10%)
  3. Conducts and analyzes sequencing data quality control and summarizes QC results to APOLLO Network investigators and Data Science Core. (10%)
  4. Maintains laboratory LIMS and electronic notebook entries and reviews accurate data entries for APOLLO Network reporting. (10%)
  5. Assists with the report of experimental results for publication in technical and peer-reviewed journals. Contributes and edits data, text and figures in program publications. (15%)
  6. Purchases, inventories, and maintains integrity of sequencing core consumables. Evaluates new sequencing kits for APOLLO Network use. (10%)
  7. May perform other duties and responsibilities as assigned or directed by the supervisor. This may include attendance of and participation in required training for role.

Required Knowledge, Skills and Abilities:
  • Knowledge of complex molecular biology laboratory procedures and ability to troubleshoot complex technical procedures required.
  • Experience with next-generation sequencing platforms (preferably Illumina) required.
  • Experience with nucleic acid isolation, properties, handling and quality control preferred.
  • Experience with robotic automated liquid handling platforms preferred.
  • Ability to work independently and supervise others; demonstrated ability to work effectively as part of a team in a deadline-driven environment; good communication and analytical skills.

Minimum Education: Doctoral degree in Molecular Biology or related field is required.

Minimum Experience/ Training Requirements: 5-8 years of relevant experience required.

Work Environment: Set in an office and laboratory work environment.

Background/Security: U.S. citizenship required; eligible to obtain and maintain a Tier III Investigation/ Secret Clearance and Common Access Card (CAC).

Employment with HJF is contingent upon successful completion of a background check, which may include, but is not limited to, contacting your professional references, verification of previous employment, addresses, education, and credentials, a criminal background check, drug screening, and a department of motor vehicle (DMV) check.

Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Chief Human Resources Officer.

Bethesda, Maryland

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is a global organization dedicated to advancing military medical research. We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians alike.

The not-for-profit Foundation is authorized by Congress to support research at the Uniformed Services University of the Health Sciences (USU) and throughout military medicine. Since its founding in 1983, HJF has served as a vital link between the military medical community and its federal and private partners. The Foundation’s support and administrative capabilities allow military medical researchers and clinicians to maintain their scientific focus and to accomplish their research goals effectively and efficiently.

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