Boston, Massachusetts

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and consumer health products, as well as animal health products.   Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us. Our company is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. To this end, our company is intentionally at the forefront of applying genetics, genomics, and biological data science to advance breakthrough science and drug development across therapeutic areas. 

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of people like you.  To this end, we strive to create an environment of mutual respect, encouragement and teamwork.  As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

  • The Genetics and Pharmacogenomics (GpGx) department at our research laboratory is currently seeking a Senior Scientist with extensive human genetics expertise to join an energetic team of computational biologists and wet lab scientists. Our mission in the Early Discovery Genetics group within GpGx is to identify and functionally validate novel targets anchored in human genetics that will enter our company's drug discovery pipeline for therapeutic intervention. The successful candidate will be intricately involved in the design, execution and interpretation of human genetic studies to transform discoveries into testable therapeutic hypotheses across Cardiovascular, Immunology, Ophthalmology and Neurosciences diseases areas. The successful candidate will be team-oriented, with the ability to effectively communicate and thrive in an inclusionary, integrated, and multidisciplinary work environment.  Specifically, the Senior Research Scientist will:
  • Integrate data from large human genetic datasets, including Genome-Wide Association Study (GWAS), RVAS, Quantitative Trait Loci (eQTL/pQTL) studies, and Mendelian genetics, to identify potential therapeutic targets across Cardiovascular, Immunology, Ophthalmology and Neurosciences diseases areas.
  • Participate in large academic/industry partnerships and leverage data from large biobanks (including FINNGEN, UK Biobank)
  • Ensure that our company is at the forefront of human genetics and is applying the most advanced methods and tools in this constantly evolving field.
  • Closely Collaborate with scientists in GpGx and the therapeutic areas to conceptualize, execute and apply genetics and genomics research for target identification and validation.
  • Communicate results to program teams and therapeutic area leadership.
  • Provide genetics expertise to biologists and senior leadership across disease areas.

Education: 

  • PhD., MD or MD/PhD, preferably with 3+ years of academic or industry postdoctoral experience in genetics in neuroscience, immune and/or cardiovascular-related diseases.

Required: 

  • Extensive expertise in Human genetics with a proven publication record.
  • Extensive experience in analyzing large-scale human Genetics dataset applying cutting-edge statistical genetics and bioinformatic methods.
  • Understanding of human biology and experience translating genetics findings to better understand biological mechanisms implicated in disease.
  • Proven track record of active participation in academic consortia or academic/industry partnerships
  • Strong communication, collaboration, and leadership skills including ability to distill and communicate complex genetic/genomic concepts to scientists from diverse disciplines.
  • <5% travel

Preferred:

  • Demonstrate significant knowledge of pathway and multi-omics approaches to integrated with genetic datasets for identifying causal gene(s) as potential therapeutic targets
  • Experience with integration of diverse high-throughput data types

The geographic location of this position is in Boston MA.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

INVENT.

IMPACT.

INSPIRE.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

US and Puerto Rico Residents Only:

If you need an accommodation for the application process please email us at staffingaadar@msd.com
For more information about personal rights under Equal Employment Opportunity, visit:


EEOC Poster

EEOC GINA Supplement​

OFCCP EEO Supplement

OFCCP Pay Transparency Rule

We are an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

Flexible Work Arrangements:

Shift:

Valid Driving License:

Hazardous Material(s):

Number of Openings:

1

Requisition ID:R91252

Boston, Massachusetts

Today's Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, and consumer care and animal health products, we work with customers and operate in more than 140 countries to deliver innovative health solutions. We also demonstrate our commitment to increasing access to healthcare through far-reaching policies, programs and partnerships. For more information, visit www.merck.com.

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